After baseline tensions and tonography, clofibrate (Atromid-S), 500 mg four times a day, was added to the usual glaucoma therapy of 11 patients with open angle glaucoma. Intraocular pressures and coefficients of outflow were done after one week, two weeks, and one month of therapy, and were compared with the baseline values.
No significant alterations in the intraocular pressure or coefficients of outflow were found, and it is therefore concluded that clofibrate does not appear to be a useful addition to present glaucoma therapy.
Marrs JM, Rowe KW. The Effect of Clofibrate on Open-Angle Glaucoma. Arch Ophthalmol. 1969;82(1):19–20. doi:10.1001/archopht.1969.00990020021005
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