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September 1969

Ophthalmic Manifestations of the Wiskott-Aldrich Syndrome

Author Affiliations

Bethesda, Md
From the Ophthalmology Branch, National Institute of Neurological Diseases and Stroke, and the Metabolism Branch, National Cancer Institute (Dr. Blaese) National Institutes of Health, US Departments of Health, Education, and Welfare, Bethesda, Md.

Arch Ophthalmol. 1969;82(3):322-329. doi:10.1001/archopht.1969.00990020324005

Ophthalmic disease was described in three patients with the Wiskott-Aldrich syndrome, an entity characterized by eczema, thrombocytopenia, and recurrent infections, and inherited in a sex-linked fashion. Blepharoconjunctivitis. associated with molluscum contagiosum, and herpes simplex keratitis, isolated or accompanied by disseminated mucocutaneous herpes simplex virus infection or both, were found. In 18 of the 80 cases of the Wiskott-Aldrich syndrome documented in the literature, ocular complications were present.

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