The ultrastructure of normal and diseased temporal arteries is studied. Degeneration of the smooth muscle cells in the media appeared to be the initial pathological change. Fragmentation of the elastic fibers and giant cell reaction may be secondary to the destructive changes.
Reinecke RD, Kuwabara T. Temporal Arteritis: I. Smooth Muscle Cell Involvement. Arch Ophthalmol. 1969;82(4):446–453. doi:10.1001/archopht.1969.00990020448004
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: