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November 1969

Effect of Osmotic Agents on the Vitreous Body

Author Affiliations

New York
From the Department of Ophthalmology, New York Medical College, New York.

Arch Ophthalmol. 1969;82(5):694-699. doi:10.1001/archopht.1969.00990020688019

The weight of the rabbit vitreous body is reduced by average clinical doses of hyperosmolar agents. The weight change is 2.7% with orally administered glycerol, and 3.7% and 3.9% with intravenously administered urea and mannitol respectively. This study substantiates the clinical observation that vitreous volume can be reduced by osmotic therapy.

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