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December 1969

Ocular Histopathology in Pulseless Disease

Author Affiliations

Washington, DC
From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC.

Arch Ophthalmol. 1969;82(6):784-788. doi:10.1001/archopht.1969.00990020776011

THE OCULAR manifestations of patients with ischemic cerebral disease have become more significant in the evaluation of the cerebral circulation.1-3 The consequences of complete retinal anoxia caused by total occlusion of the central retinal vessels are less important and revealing than the effects of a more chronic and subtle type of hypoxia.1 Perhaps the most striking example of chronic occlusive disease within the group of aortic arch syndromes3 is pulseless disease (Takayasu-Ohnishi's disease). Although the ocular manifestations of the disease are well known,3,4-8 the only report available on the histopathologic changes observed in the eyes is that of Dowling and Smith,9 who reported their findings in flat preparations of the retina. This report describes the histopathologic findings in a pair of eyes from a patient who died of pulseless disease.

Report of a Case 

Clinical Summary.  —(A more detailed summary of the general medical history

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