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December 1969

Stereologic Measurement of Cell Volume Fraction of Rabbit Corneal Stroma

Author Affiliations

New York
From the F. Higginson Cabot Laboratory of the Division of Surgical Pathology, departments of surgery and pathology, College of Physicians and Surgeons, Columbia University, New York.

Arch Ophthalmol. 1969;82(6):792-794. doi:10.1001/archopht.1969.00990020784013

Using stereologic techniques, electron micrographs of perinatal and adult rabbit corneal stroma were measured to determine the percent cell volume in each. The measured values of 40% (± 8.2) and 10.6% (± 3.8) for the perinatal and adult, respectively, agree well with our previously estimated values of 50% and 12.5%. The figure for the adult corneal stroma is two to three times that reported by others and should provide a more precise base for evaluating measurements of electrolyte concentrations in the corneal stroma.