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April 1970

Vitreous Hemorrhage: An Experimental Study: I. A Macroscopic and Isotopic Study of the Evolution of Whole Blood and Hemoglobin

Author Affiliations

From the Department of Retina Research, Retina Foundation, Boston, and the Foundation of Medical Research, Paris. Dr. Regnault is a senior research fellow under the Fulbright-Hays program.

Arch Ophthalmol. 1970;83(4):458-465. doi:10.1001/archopht.1970.00990030458014

Through photographic and isotopic analysis, this study of experimental intravitreous hemorrhages traces the fate of red blood cells after injection of whole blood and hemoglobin into rabbit vitreous. The vitreous is almost entirely translucent two months after hemoglobin injection, but 25% of ferric chloride Fe59 remains within the eye. Comparing photographs of experimental intravitreous hemorrhages with spontaneous intravitreal hemorrhages in humans shows that the two types are similar.

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