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May 1970

Acquired Sixth-Nerve Paresis in Children

Author Affiliations

Rochester, Minn
From the Section of Ophthalmology, Mayo Clinic and Mayo Foundation (Drs. Robertson and Rucker), and the Mayo Graduate School of Medicine (Dr. Hines), Rochester, Minn.

Arch Ophthalmol. 1970;83(5):574-579. doi:10.1001/archopht.1970.00990030574008

In a review of 133 cases of isolated acquired sixth-nerve paresis in the pediatric age group, six etiologic categories were analyzed separately. More than a third of the cases were due to tumor; in the cases of tumor it was frequently noted that there was a history of trauma or there were findings suggestive of an infectious process. Of the ten cases with Gradenigo's syndrome, three were later discovered to have tumor. The presence of chronic papilledema and fifth-nerve involvement suggested tumor. Though the prognosis for the tumor group was poor, the patients whose disorder was due to trauma or inflammation often had complete spontaneous resolution of the nerve paresis.

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