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August 1970

Bacterial Cultures From Donor CorneasA Study of Eyes Treated With Thimerosal Solution Prior to Corneal Grafting

Author Affiliations

New York
From the New York Eye and Ear Infirmary, 310 E 14 St, New York.

Arch Ophthalmol. 1970;84(2):148-150. doi:10.1001/archopht.1970.00990040150005

One-hundred donor eyes were removed with aseptic precautions and bathed in a solution of thimerosal before corneal grafting. With this treatment, there was an incidence of only 22% positive bacterial cultures, one-half of which were considered potentially pathogenic. This suggests that thimerosal is an effective antibacterial agent. Antibiotic solutions, in particular those containing neomycin sulfate and polymyxin B sulfate, appear to be more specific than thimerosal and may be used as a replacement for the latter or in conjunction with it in treating donor eyes prior to corneal grafting.