[Skip to Navigation]
September 1970

Metastatic Uveal Choriocarcinoma: Report of a Case With Improvement After Chemotherapy

Author Affiliations

Columbus, Ohio
From the Department of Ophthalmology, Ohio State University, Columbus, Ohio. Dr. Billig is a postdoctoral fellow from the National Institutes of Health.

Arch Ophthalmol. 1970;84(3):381-384. doi:10.1001/archopht.1970.00990040383020

A 19-year-old pregnant woman with weight loss and pulmonary infiltrates was found to have metastatic choriocarcinoma. A concomitant marked visual loss was associated with multiple elevated choroidal lesions in both eyes. Treatment with methotrexate resulted in clinical remission and striking improvement of vision and fundus appearance.