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December 1970

Studies on Experimental Ocular Toxoplasmosis in the Rabbit: II. Attempts to Stimulate Recurrences by Local Trauma, Epinephrine, and Corticosteroids

Author Affiliations

San Francisco
From the Francis I. Proctor Foundation for Research in Ophthalmology and the Department of Ophthalmology, University of California Medical Center, San Francisco.

Arch Ophthalmol. 1970;84(6):788-791. doi:10.1001/archopht.1970.00990040790019

Attempts to reactivate healed, experimentally induced toxoplasmic retinochoroiditis in the rabbit were unsuccessful. Three possible causes of recurrence of human toxoplasmic lesions were evaluated: blunt local trauma, systemically administered epinephrine, and systemically administered corticosteroids. In no case could reactivation be observed ophthalmoscopically. However, minimal round cell infiltration was seen in histologic preparations from the eyes of hydrocortisone-treated animals.

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