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December 1970

Studies on Experimental Ocular Toxoplasmosis in the RabbitII. Attempts to Stimulate Recurrences by Local Trauma, Epinephrine, and Corticosteroids

Arch Ophthalmol. 1970;84(6):788-791. doi:10.1001/archopht.1970.00990040790019

Attempts to reactivate healed, experimentally induced toxoplasmic retinochoroiditis in the rabbit were unsuccessful. Three possible causes of recurrence of human toxoplasmic lesions were evaluated: blunt local trauma, systemically administered epinephrine, and systemically administered corticosteroids. In no case could reactivation be observed ophthalmoscopically. However, minimal round cell infiltration was seen in histologic preparations from the eyes of hydrocortisone-treated animals.