THE PURPOSE of this paper is to report the peculiar ocular histopathologic changes of an anomalous cleavage of the anterior chamber angle, choristomatous cornea-like tissue on the anterior iris surface, and a membrane in the chamber angle in an infant with multiple congenital anomalies.
Report of a Case
This 2-month-old white female infant died at St. Christopher's Hospital for Children on Jan 9, 1967 (autopsy: A-3-67; Wilmer Eye Pathology 29294). The infant's body was grossly malformed, exhibiting generalized asymmetry. The body weighed 2,124 gm (4 lb 10½ oz). The head was markedly flattened on the right side; the fontanel was located above the midportion of the left eyebrow rather than in the midline. The right eye bulged forward considerably. The pupil of the right eye was irregular, and the iris near the pupil had a rim of whitish tissue around it. The left eye was considered normal. The mandible
Karlsberg RC, Emery JM, Green WR, Valdes-Depena M, Coulombre AJ. Anomalies of Iris and Anterior-Chamber Angle: Occurrence in a Child With Multiple Congenital Anomalies. Arch Ophthalmol. 1971;86(3):287–292. doi:10.1001/archopht.1971.01000010289009
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.