FEAR of enhancing fungal growth has prohibited the use of local administration of corticosteroid in the treatment of keratomycosis,1-4 although its value in the therapy of other forms of microbial-induced inflammatory corneal disease is well documented.5,6 This case report describes the management of a deep corneal abscess which followed trauma. Combined corticosteroid-antifungal therapy followed by penetrating keratoplasty was successful in eliminating the fungal infection and attaining useful vision.
Report of a Case
The patient, aged 23, was struck in the right eye by a strand of barbed wire while serving as a noncombatant in Vietnam. Although his vision immediately blurred and he experienced some pain, he did not seek medical attention until two days later. He was immediately admitted to the hospital with the diagnosis of hypopyon ulcer, and for the next three weeks he was treated with locally and systemically administered medications that included a variety of
Denis M. O'Day, Thomas E. Moore, Samuel B. Aronson. Deep Fungal Corneal AbscessCombined Corticosteroid Therapy. Arch Ophthalmol. 1971;86(4):414–419. doi:10.1001/archopht.1971.01000010416010