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March 1972

The Eye in Systemic Disease, III (International Ophthalmology Clinics

Arch Ophthalmol. 1972;87(3):364. doi:10.1001/archopht.1972.01000020366031

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This volume comprises five chapters of varying length.

Medicolegal aspects of adverse drug reactions are considered by Howard N. Bernstein and Aaron M. Levine. The manufacturer's duty to warn is related to the physician's responsibility to be aware of a drug's hazards, to use drugs for a rational purpose, and to obtain informed consent when doing clinical investigation. These precepts are illustrated by appropriate references to situations arising in ophthalmic practice.

Antimicrobial therapy in ophthalmology, as discussed by Raymond E. Records, is a comprehensive review of the basic properties, mode of action, side effects, and clinical use of sulfonamides and antibiotics. Several useful tables and charts enhance the descriptive text. Mechanisms of bacterial resistance to antimicrobial agents are especially well illustrated. Dosage schedules and routes of administration are presented. In mentioning the action of blocking agents, the author does not mention the inhibition of the ciliary body's excretion of penicillin

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