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June 1972

Electrophysiologic and Fluorescein Studies in Vitelliform Macular Degeneration

Author Affiliations

San Francisco
From the Department of Ophthalmology, Pacific Medical Center, and the Smith-Kettlewell Institute of Visual Sciences, San Francisco.

Arch Ophthalmol. 1972;87(6):636-641. doi:10.1001/archopht.1972.01000020638005

Clinical findings, electrophysiologic studies, and fluorescein angiography are reported in a family pedigree with vitelliform macular degeneration. The electrooculogram is the most useful diagnostic test in this condition. It is also helpful prognostically as an aid in identifying the carrier state. Fluorescein angiography demonstrates a vascular anomaly not previously reported in vitelliform macular degeneration. These may participate in clearing hemorrhage, exudate, and edema from the macular area, resulting in improved visual acuity. The significance of early filling of the superior arterial trunks (noted in two patients) was not determined, but suggests a connection between the choroidal and arterial circulation.

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