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August 1972

Side Effects of Drugs in Ophthalmology: International Ophthalmology Clinics

Arch Ophthalmol. 1972;88(2):233. doi:10.1001/archopht.1972.01000030235030

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This slender volume is written largely by members of the Department of Ophthalmology, University of Colorado. The first chapter by Ellis deals with systemic reactions to commonly used topically administered drugs such as atropine, epinephrine, cholinesterase inhibitors, etc. This is followed by a summary of side effects of drugs on the cornea, conjunctiva, and the extraocular muscles. The chapter by Patterson is an excellent review of the effects of drugs on the lens, in which the author tries to delineate the biochemical mechanisms involved in the action of these drugs. This is followed by chapters on aqueous humor dynamics, the retina, and the optic nerve. The last chapter by Lipson is a useful compilation of the toxicity of systemic drugs.

The value of this book would have been enhanced if current thoughts on the biochemical pharmacology and therapeutics of some of these drugs had been included.

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