Two patients with lacrimal sarcoidosis showed improvement on alternate day prednisone therapy. One patient had keratitis sicca and became asymptomatic after treatment, demonstrating a return to normal visual acuity, increased tear production, and disappearance of corneal staining. The second patient had greatly enlarged lacrimal glands which were a cosmetic problem and led to the erroneous diagnosis of glaucoma. The lacrimal glands in this patient returned to near normal size following a course of prednisone.