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January 1973

Immunoglobulins in the Human Eye: Location, Type, and Amount

Author Affiliations

Stanford, Calif
From the Department of Surgery/Ophthalmology, Stanford School of Medicine, Stanford, Calif.

Arch Ophthalmol. 1973;89(1):36-45. doi:10.1001/archopht.1973.01000040038010

Immunoglobulins were found in all structures of the eye except the lens. The highest concentrations (up to one-half the amount in serum) were found in the cornea, choroid, and conjunctiva. Moderate concentrations were found in the muscle and sclera. Low concentrations (less than 5% of the serum level) were found in the ciliary body, iris, aqueous, and retina. All five immunoglobulins and albumin were present in the immunoglobulin-containing tissues except for the cornea, which did not routinely contain IgM.

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