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April 1973

Retinal Vessels in Down's Syndrome

Author Affiliations

Vancouver, British Columbia, Canada; New Westminster, British Columbia, Canada
From the Department of Ophthalmology (Drs. Williams and McCormick), Vancouver General Hospital, Vancouver, British Columbia, Canada, and Woodlands School, Residential Setting for Retarded, New Westminster, British Columbia, Canada (Dr. Tischler).

Arch Ophthalmol. 1973;89(4):269-271. doi:10.1001/archopht.1973.01000040271001

The fundus vessels of 50 institutionalized mongols were compared with the fundus vessels of 50 sex-matched controls of similar age. Mongols appear to have significantly more retinal vessels crossing the margin of the optic nerve head. The high number of vessels is associated with an unusual, spoke-like appearance of the retinal vasculature and may be helpful in the clinical diagnosis of Down's syndrome (mongolism) in the newborn.