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May 1973

Optic Nerve Drusen

Author Affiliations

Los Angeles
From the departments of ophthalmology (Drs. Kamin and Hepler) and pathology (Dr. Foos), Jules Stein Eye Institute, UCLA School of Medicine, Los Angeles.

Arch Ophthalmol. 1973;89(5):359-362. doi:10.1001/archopht.1973.01000040361001

Two case reports, one clinical and the other pathologic, illustrate important features of optic nerve drusen. A clinical subject demonstrates that optic nerve drusen cause visual field defects and central visual loss in childhood. Another case, studied postmortem, illustrates optic atrophy caused by drusen. Optic nerve drusen may originate from coalescing intracellular deposits of glial cells.