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May 1973

Neuroectodermal Tumor of Anterior Lip of the Optic Cup: Glioneuroma Transitional to Teratoid Medullo-epithelioma

Author Affiliations

Kingston, Ontario, Canada
From the departments of pathology (Drs. Manz and Macklin) and ophthalmology (Drs. Rosen and Willis), Queen's University and affiliated hospitals, Kingston, Ontario, Canada.

Arch Ophthalmol. 1973;89(5):382-386. doi:10.1001/archopht.1973.01000040384006

A congenital neoplasm of the inner layer of the anterior lip of the optic cup is delineated. Because of continued growth, local excision was performed at 6 months of age, followed by cardiac arrest. The neoplasm demonstrates features predominantly of a glioneuroma, but with transitions to a teratoid medullo-epithelioma. Local invasion of iris, ciliary body, trabecular meshwork, retina, and sclera was apparent. An associated finding was persistence of the primary vitreous and hyaloid artery in the opposite eye.

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