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Article
May 1973

Glioneuroma (Choristomatous Malformation of the Optic Cup Margin)A Report of Two Cases

Author Affiliations

San Francisco
From the Department of Ophthalmology, Eye Pathology Laboratory, University of California, San Francisco.

Arch Ophthalmol. 1973;89(5):387-391. doi:10.1001/archopht.1973.01000040389007
Abstract

The clinical and pathologic features of two congenital tumors are delineated and discussed. Each tumor is composed of glial and neuronal elements and appears to arise within colobomatous defects in the ciliary body, iris, and retina. These benign tumors resemble well-differentiated mature brain tissue, and are believed to represent choristomatous malformations developed from divergent differentiation of the neuroepithelial cells at the advancing margin of the invaginated optic cup.

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