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July 1973

Werner Syndrome

Author Affiliations

New Haven, Conn
From the Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Conn.

Arch Ophthalmol. 1973;90(1):53-56. doi:10.1001/archopht.1973.01000050055011

Findings are reported for a 47-year-old man with Werner syndrome. He is prematurely old, has diabetes mellitus of adult onset, skin atrophy, poliosis, and characteristic posterior subcapsular cataracts. Additional ocular features compatible with premature aging in this man include diminished tear flow, arcus senilis, and reduced accommodation. Slight venous tortuosity, and mild leakage of fluorescein in the macular area of each eye were the only minimal findings suggestive of diabetic retinopathy. Cataract surgery in these patients may be hazardous.