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March 1974

Paralysis of Down-Gaze

Author Affiliations

From the Howe Laboratory of Ophthalmology, Harvard University Medical School, and Massachusetts Eye and Ear Infirmary, Boston.

Arch Ophthalmol. 1974;91(3):192-199. doi:10.1001/archopht.1974.03900060200009

The significance of down-gaze paralysis was evaluated in a study of 30 patients. Four categories were identified: (1) a reverse Parinaud syndrome (four cases) in which the lesion was either presumed to be or demonstrated to be present beneath the central gray matter of the anterior mesencephalon; (2) those cases associated with various choreo-athetotic syndromes (seven cases); (3) parkinsonoid syndromes (16 cases); and (4) miscellaneous group (three cases).