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June 1974

Electric Cataracts: III. Animal Model

Author Affiliations

Little Rock, Ark
From the departments of ophthalmology and pharmacology, University of Arkansas Medical Center, Little Rock.

Arch Ophthalmol. 1974;91(6):469-473. doi:10.1001/archopht.1974.03900060483011

The typical electric cataract seen in man was produced by passage of 28 to 150 watt-seconds of electrical energy through the rabbit eye. Lens vacuoles appeared initially, increased in size, and gradually disappeared, and were replaced by anterior subcapsular cataracts. Ultrastructurally the vacuoles were located between the epithelial cells. As the vacuoles disappeared the surrounding epithelium began to divide and to differentiate into small lens fibers. These new fibers produced new lens capsule material. In time the individual fibers produced opaque plaques that coalesced to form a central elevated anterior subcapsular cataract.