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August 1974

Low-Dose Epinephrine: Effect on Intraocular Pressure

Author Affiliations

St. Louis
From the Department of Ophthalmology, Washington University School of Medicine, St. Louis.

Arch Ophthalmol. 1974;92(2):118-120. doi:10.1001/archopht.1974.01010010124008

The effect of low doses of epinephrine hydrochloride on intraocular pressure was evaluated. Concentrations of ⅛%, ¼%, ½% and 1% epinephrine were administered to one eye of a patient over a four-week period. An interval of four weeks was allowed before the successive higher concentration was applied. The fellow eye was left untreated and served as a control. The results indicate that epinephrine lowers intraocular pressure at the concentrations tested with significantly greater effectiveness at the higher dose levels.

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