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September 1974

Synthesis of a Collagenous Basal Membrane by Rabbit Corneal Endothelial Cells in Vitro

Author Affiliations

From the Department of Ophthalmology, New England Center Hospital, and Tufts University School of Medicine, Boston.

Arch Ophthalmol. 1974;92(3):238-239. doi:10.1001/archopht.1974.01010010246015

Synthesis of a basal lamina was observed in monolayer cultures of rabbit corneal endothelium. This material resembles Descemet membrane in appearance, staining properties, and collagen content. This communication demonstrates, for the first time, the in vitro production of a Descemet-like basal lamina by corneal endothelial cells.

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