A 17-year-old white male subject with phlyctenular keratitis, superficial candidiasis, and hypoparathyroidism was found to be anergic in delayed hypersensitivity. Reconstitution of the cell-mediated immune response to Candida albicans by means of allogeneic lymphocyte transfusion and by means of transfer factor, and amphotericin B promptly resulted in the clinical remission of the phlyctenulosis and chronic candidiasis.
Wong VG, Kirkpatrick CH. Immune Reconstitution in Keratoconjunctivitis and Superficial Candidiasis: The Role of Immunocompetent Lymphocyte Transfusion and Transfer Factor. Arch Ophthalmol. 1974;92(4):335–339. doi:10.1001/archopht.1974.01010010345018
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