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October 1974

Misconception About Chelation-Reply

Arch Ophthalmol. 1974;92(4):362. doi:10.1001/archopht.1974.01010010372029

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To the Editor.  —I think Drs. Davis and Chandler are right as far as they go, but they say "one recent text" correctly identified these substances, without mentioning that I made it all very clear in my Toxicology of the Eye.Further, the authors should give attention to the article by Berman and Manabe (Ann Ophthalmol 5:1193, 1973) in which they give evidence that not only calcium but zinc is involved in the activity of some collagenases, and in this context, one might use either calcium or sodium EDTA.

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