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July 1975

Ocular Anti-inflammatory Effect of Fenoprofen: Dose-Response Study

Author Affiliations

From New York Hospital, Society of the New York Hospital, New York.

Arch Ophthalmol. 1975;93(7):501-503. doi:10.1001/archopht.1975.01010020517006

An experimental rabbit uveitis model was used to establish a dose response range for topical administration of fenoprofen (dl-2-(3-phenoxyphenyl) propionic acid. The 0.3% concentrate group was not distinguishable from the untreated group, and 3% concentrate proved highly irritating. Fenoprofen 1%, pH 6.4, proved most efficacious and had an effect comparable to dexamethasone phosphate 0.1%, seen in a previous study.

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