• A 33-year-old man had a two-year history of uveitis associated with a primary reticulum cell sarcoma of the brain. At autopsy, inflammatory cells were present throughout the vitreous and no intraocular reticulum cell sarcoma was present.
The pathogenesis of this cellular reaction is obscure, but the reaction may precede the infiltration of the eye by malignant reticulum cells. It is important to recognize the association of uveitis and neurologic signs as radiotherapy may substantially prolong life in patients with this association.
Kennerdell JS, Johnson BL, Wisotzkey HM. Vitreous Cellular ReactionAssociation With Reticulum Cell Sarcoma of Brain. Arch Ophthalmol. 1975;93(12):1341–1345. doi:10.1001/archopht.1975.01010020967006
* * SCHEDULED MAINTENANCE * *
The JAMA Network Sites will be conducting routine maintenance from 10/20/2017 through 10/21/2017. During this window access to content and authentication may be intermittently available. The JAMA Store will be completely unavailable during the maintenance window.