In a child with a hypothalamic glioma, elevated intracranial pressure and retrograde optic tract atrophy produced distinctive patterns of papilledema and disc pallor in each eye. On the side of the tract lesion, the disc was swollen nasally and was pale temporally. In the contralateral fundus, the swollen optic disc was bisected horizontally by a pale atrophic band. These funduscopic signs exemplify a rare instance in neuro-ophthalmologic diagnosis wherein specific lateralizing and localizing information can be deduced solely from the appearance of papilledema.
Paul TO, Hoyt WF. Funduscopic Appearance of Papilledema With Optic Tract Atrophy. Arch Ophthalmol. 1976;94(3):467–468. doi:10.1001/archopht.1976.03910030237013