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This book is the record of a symposium on the treatment of chronic intractable pain organized by the Department of Neurological Surgery at Rush-Presbyterian-St Luke's Medical Center in Chicago in February 1973. It discusses the use of drugs, hypnosis, and acupuncture and various ways of making pain-relieving lesions in the nervous system—cordotomy, rhizotomy, sympathectomy, mesencephalotomy, thalamotomy, and cingulotomy.