• In vitro studies have demonstrated a relative resistance of herpes simplex virus type 2 to antiviral therapy when compared with herpes simplex virus type 1. The in vivo studies, however, show an excellent therapeutic response to both antiviral drugs in experimentally induced viral keratoconjunctivitis.
North RD, Pavan-Langston D. Herpes Simplex Virus Types 1 and 2: Therapeutic Response to Antiviral Drugs. Arch Ophthalmol. 1976;94(6):1019–1021. doi:10.1001/archopht.1976.03910030517015
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