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August 1976

Treatment of Vaccinial Keratitis With Vidarabine

Author Affiliations

From the Francis I. Proctor Foundation for Research in Ophthalmology and the Department of Ophthalmology, University of California, San Francisco (Dr Smolin and Mr Okumoto); the Cornea-External Disease Unit, Department of Ophthalmology, Medical College of Wisconsin, Milwaukee (Drs Hyndiuk and Damiano); and the Institute of Ophthalmology, University of the Philippines, Manila (Dr Valenton).

Arch Ophthalmol. 1976;94(8):1363-1364. doi:10.1001/archopht.1976.03910040235016

• Vaccinial epithelial keratitis was produced in rabbits. When the therapeutic effect of vidarabine on the experimentally-induced disease was evaluated and compared to the effect of idoxuridine, vidarabine was found to be highly effective, substantially more effective than idoxuridine, and nontoxic to the eye.

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