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October 1976

Phakomatous Choristoma of Eyelid: Electron Microscopical Confirmation of Lenticular Derivation

Author Affiliations

From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC.

Arch Ophthalmol. 1976;94(10):1778-1781. doi:10.1001/archopht.1976.03910040552014

• This article presents the sixth recorded example of phakomatous choristoma of the eyelid. The tumor occurred in a 4-month-old boy and was located in the lower lid near the inner canthus. The findings from light microscopy included epithelial, tubular structures with associated patches of thick, irregular basement membrane. The results of electron microscopy (ie, epithelial cells with a scarcity of organelles, homogeneous type of basement membrane, cytoplasmic microfilaments, segments of fascia occludens, and degenerated cells with peculiar interdigitations of their plasmalemmas) are all consistent with lenticular derivation, as originally proposed by Zimmerman.1