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October 1976

Endogenous Candida Endophthalmitis Associated With Heroin Use

Arch Ophthalmol. 1976;94(10):1805. doi:10.1001/archopht.1976.03910040579023

To the Editor.  —During November 1975 through February 1976 we treated four cases of endogenous Candida endophthalmitis in heroin addicts. In addition, a similar case has been treated at a neighboring medical center in Chicago. These are the only cases of the disease that have been recognized at the University of Illinois Eye and Ear Infirmary during the last five years and possibly represent a small epidemic of the disease in heroin addicts. Endogenous Candida endophthalmitis also is a well-recognized complication in patients who are undergoing hyperalimentation,1 who need complicated abdominal surgical procedures,2 and who have debilitating diseases.3,4The systemic effects of heroin addiction and its association with bacterial and fungal endocarditis have been well established.5 The first case of fungal endophthalmitis associated with heroin addiction was reported by Sugar et al6 in 1971. Subsequent cases caused by Candida species have been reported.7,8 If