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July 1977

Untreated Ocular Hypertension: A Long-Term Prospective Study

Author Affiliations

From the Department of Ophthalmology, University of Tokyo School of Medicine (Drs Kitazawa and Horie); Department of Ophthalmology, Chiba (Japan) University School of Medicine (Dr Aoki); and the Department of Ophthalmology, Juntendo (Japan) University School of Medicine (Drs Suzuki and Nishioka).

Arch Ophthalmol. 1977;95(7):1180-1184. doi:10.1001/archopht.1977.04450070078004

• A prospective study was designed to determine the course of ocular hypertension without visual field loss if untreated and to estimate the value of various clinical findings in predicting the course of ocular hypertension. Seventy-five patients with intraocular pressure greater than 21 mm Hg but without demonstrable visual field defects were followed up without glaucoma therapy for a minimum of nine years. While under observation, seven of 75 ocular hypertensives developed typical glaucomatous visual field defects. Both the sensitivity and the specificity of each clinical finding in the individuals who later developed visual field defects were determined, and none of the clinical findings was found to be a good predictive indicator.

(Arch Ophthalmol 95:1180-1184, 1977)

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