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December 1977

Calmette-Guerin Bacillus Treatment of Experimental Conjunctival Malignant Melanoma

Author Affiliations

From the Department of Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago.

Arch Ophthalmol. 1977;95(12):2214-2217. doi:10.1001/archopht.1977.04450120120017

• Malignant melanoma of the conjunctival region was induced in the golden Syrian hamster. Inoculation of this lesion with Calmette-Guerin bacillus (BCG), 48 hours after injection of 103 tumor cells, either slowed, limited, or completely prevented the growth of the tumor in 56% of the treated eyes. In 98% of the control eyes, malignant melanoma grew rapidly and extensively.

(Arch Ophthalmol 95:2214-2217, 1977)

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