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February 1979

The Use of Phenylephrine in Eyelid Cryosurgery

Arch Ophthalmol. 1979;97(2):359-360. doi:10.1001/archopht.1979.01020010195027

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To the Editor.  —During the past two years we have performed cryosurgery on more than 250 eyelids for aberrant lashes. Many of these eyelids have required ablation of all lashes. Most of these cases result from the trichiasis or acquired distichiasis that can occur in cases of ocular pemphigoid, Stevens-Johnson syndrome, chronic miotic therapy, or chemical or physical injuries to the eyelids. In some cases no cause was found. We use a freeze-thaw-refreeze cycle that obtains −20 °C to −25 °C at the base of the lash follicles twice. The tissues are allowed to return to room temperature between freezes. A thermocouple placed at the base of the lash follicles is used to carefully monitor temperatures. In cases where total eyelid ablation is performed, a considerable time period may be required to obtain the necessary temperature in all locations along the eyelid to kill the lash follicles. This time can

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