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March 1979

Corynebacterium EndophthalmitisLaboratory Studies and Report of a Case Treated by Vitrectomy

Author Affiliations

From the Department of Ophthalmology, Jules Stein Eye Institute, UCLA School of Medicine, Los Angeles. Dr Hanscom is in receipt of the Charles K. Feldman Fellowship.

Arch Ophthalmol. 1979;97(3):500-502. doi:10.1001/archopht.1979.01020010250013

• A Corynebacterium sp was isolated from the vitreous humor under aseptic conditions on two separate occasions from a patient with endophthalmitis resulting from a penetrating injury by a metallic foreign body. The metallic foreign body was removed during a pars plana lensectomy and anterior vitrectomy procedure; intravitreously injected methicillin sodium, gentamicin sulfate, and dexamethasone sodium phosphate gave a functional visual result. Intravitreous inoculation of rabbits with the Corynebacterium isolate produced an endophthalmitis similar to that produced in the patient, and subsequent cultures from the vitreous of the inoculated rabbits grew the same Corynebacterium sp. To our knowledge, this is the first reported case of endophthalmitis in which a Corynebacterium sp was documented by intraocular culture.