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July 1979

The Electroretinogram in Retinitis Pigmentosa

Author Affiliations

From the Division of Ophthalmology, Stanford (Calif) University School of Medicine, and the Ophthalmology Section, Veterans Administration Hospital, Palo Alto, Calif.

Arch Ophthalmol. 1979;97(7):1300-1304. doi:10.1001/archopht.1979.01020020042009

• Examination of electroretinographic (ERG) reports from 70 consecutive patients with retinitis pigmentosa (RP) showed that photopic and scotopic B-wave amplitudes correlated with age and visual acuity, but not with dark adaptation threshold. No appreciable differences in ERG characteristics (including B-wave implicit time) were observed between recessive, dominant, and X-linked cases. However, the ERG findings from one group of patients stood out clearly from the rest, because of normal flicker B-wave implicit times (≤ 32 ms) and large B-wave amplitudes (≥ 100 μV under scotopic conditions). These patients constitute a recognizable subgroup of RP, independent of the mode of inheritance, which is characterized by delimited disease, mild functional symptoms, and a good visual prognosis.