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July 1979

Experimental Model for Scleritis

Author Affiliations

From the Strangeways Research Laboratory, Cambridge, England. Dr Playfair is now with the Department of Ophthalmology, University of Sydney, Sydney Eye Hospital, Sydney, Australia.

Arch Ophthalmol. 1979;97(7):1337-1340. doi:10.1001/archopht.1979.01020020079019

• Rabbits were sensitized over a prolonged period to ovalbumin by intradermal injection. Ovalbumin was then injected into the limbus of the eye. A corneoscleral lesion, similar to necrotizing scleritis in humans, was produced. The clinical progression of this lesion is described and its histologic appearance discussed in relation to the human disease.

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