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August 1979

Fusarium Oxysporum Endophthalmitis

Author Affiliations

Nashville, Tenn

Arch Ophthalmol. 1979;97(8):1545. doi:10.1001/archopht.1979.01020020195034

To the Editor.  —The article by Rowsey et al entitled "Fusarium Oxysporum Endophthalmitis" in the January Archives (97:103-105, 1979) raises some interesting points that deserve comment.A diagnosis of fungal infection was made initially when macroconidia, typical of Fusarium sp, were identified on a smear of material obtained at vitrectomy. This is a somewhat unusual circumstance, as we are not aware of Fusarium sporulation in mammalian tissue. It raises the possibility that these spores may have been part of the original inoculum. We would, therefore, be very interested to learn if hyphal material were seen on smear, because this would indicate with certainty that fungal proliferation had occurred within the eye. In the absence of hyphal material, the fascinating possibility needs to be considered that the spores inoculated at the time of injury failed to germinate within the eye, although they remained viable. Germination occurred only when they were

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