• Complications occurred after 360° prophylactic cryoretinopexy in three of six eyes in which fellow eyes had previously developed aphakic retinal detachment. Two of the six prophylactically treated eyes developed retinal detachment in advance of anticipated cataract surgery, and a third developed vitreitis and progressive preretinal membrane formation after uncomplicated cataract extraction. In an experimental study with rhesus monkeys, preretinal membrane formation was produced by administering heavy freezes with 360° cryoretinopexy. Although the quantities of cold were considered excessive for clinical use, the cryoretinopexy used clinically in this series must also be considered excessive. The use of 360° cryoretinopexy in the management of eyes at high risk for retinal detachment must be considered judiciously. Particular caution must be exercised in administering cryoretinopexy to nondetached retinas so as to avoid heavy freezes, which destroy the inner retinal layers.
Robertson DM, Priluck IA. 360° Prophylactic Cryoretinopexy: A Clinical and Experimental Study. Arch Ophthalmol. 1979;97(11):2130–2134. doi:10.1001/archopht.1979.01020020448007
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