• We produced chronic experimental herpetic keratitis by dropping PH-strain herpes simplex virus on scarified rabbit corneas and then injecting the rabbits subconjunctivally with low doses of corticosteroid (namely, triamcinolone acetonide suspension). Vitamin-A-treated rabbits developed milder, more rapidly healing epithelial lesions than untreated rabbits. Whereas most of the untreated rabbits developed moderate or severe stromal disease, most of the vitamin-A-treated rabbits developed only mild stromal disease or none at all.
Smolin G, Okumoto M, Friedlaender M, Kwok S. Herpes Simplex Keratitis Treatment With Vitamin A. Arch Ophthalmol. 1979;97(11):2181–2183. doi:10.1001/archopht.1979.01020020499019
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