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Article
February 1980

Juvenile Fibromatosis of the Periorbital Region and Eyelid: A Clinicopathologic Study of Six Cases

Author Affiliations

From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC.

Arch Ophthalmol. 1980;98(2):280-285. doi:10.1001/archopht.1980.01020030276007
Abstract

• Six cases of juvenile fibromatosis of the periorbital region and eyelid were studied. The median age of the patients was 8 years (range, 1 to 11 years). A definite propensity for involvement of the infraorbital region and lower eyelid was observed. Three tumors exhibited a prominent lobular pattern and were adherent to the periosteum. The main entities in the differential diagnosis included leiomyoma, neurofibroma, and well-differentiated fibrosarcoma. Two of six tumors recurred locally but did not metastasize. Electron microscopic studies disclosed that the spindle-shaped tumor cells exhibited features of fibroblasts. It appears that conservative treatment (ie, local excision) is adequate.

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