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Article
February 1980

Visually Evoked Potentials to Pseudorandom Binary Sequence StimulationPreliminary Clinical Trials

Author Affiliations

From the Department of Ophthalmology, Southwestern Medical School, University of Texas, and the Callier Center for Communication Disorders, Dallas.

Arch Ophthalmol. 1980;98(2):296-298. doi:10.1001/archopht.1980.01020030292010
Abstract

• We report results using a new stimulus for clinical testing of visually evoked potentials (VEPs). The stimulus was the modulation of the luminance of a large unpatterned field by a temporal pseudorandom binary sequence. The stimulus was similar to Gaussian white noise in that a large number of sinusoidal harmonics were presented concurrently. It has the important advantage that conventional signal averaging techniques can be used to analyze the VEP. Abnormal VEP responses were obtained when the stimulus was applied to patients with minimal macular and optic nerve disease.

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