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February 1980

Persistent Infection of a Posttraumatic Phycomycotic Infection

Author Affiliations

San Francisco

Arch Ophthalmol. 1980;98(2):383-384. doi:10.1001/archopht.1980.01020030379028

To the Editor.  —In May 1978, Schwartz et al1 documented the ocular effects of a posttraumatic phycomycotic infection on the anterior segment of the left eye of a 26-year-old man. We now wish to report follow-up clinical data and histologic evidence of localized persistence of the infection in the anterior segment and donor cornea two years later.The patient initially manifested a Rhizopus (phycomycosis) infection of the anterior segment of his left eye two months following a perforating injury with a soil-contaminated screwdriver. After intensive but unsuccessful antifungal medical therapy, a combined 10-mm penetrating keratoplasty and planned extracapsular cataract extraction was performed (Jan 7, 1977), which included the removal of an organized anterior chamber cast and portions of necrotic iris. Postoperatively, the patient received a seven-day course of intravenous amphotericin B and topical natamycin drops, and was discharged from the hospital on Jan 25, 1977, with a clinically quiet

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